Phytochemical screening and antihelminthic activity of leaf and root extracts of Cassia tora plant

Authors

  • Aashish Shrestha Department of Pharmacy, Sunsari Technical College, Dharan
  • Kamana Ghimire Department of Pharmacy, Sunsari Technical College, Dharan
  • Amit Kumar Gupta Department of Pharmacy, Sunsari Technical College, Dharan
  • Priyanka Pokhrel Department of Pharmacy, Sunsari Technical College, Dharan
  • Janmajoy Banerjee Department of Pharmacy, Sunsari Technical College, Dharan
  • Hemanta Khanal Central campus of Technology Hattisar , Dharan
  • Mahalaxmi Pradhananga Central campus of Technology Hattisar , Dharan

Keywords:

Cassia tora, Citrobacter koseri, Staphylococcus aureus, Pheretima posthuma

Abstract

Cassia tora is one of the most important sources of medicinally important phytochemicals and widely used in Ayurvedic and Chinese system of medicine. The fresh plants of cassia tora were collected from the different locality of Dharan, Sunsari district during the month of August. In this study leaves and root extracts were subjected to extraction by soxheletion by using ethanol and water and the extracts were subjected to antibacterial activity against Staphylococcus aureus. and Citrobacter koseri, the ethanolic extracts were screened for antihelmenthic activity against Indian adult earth worm (Pheretima posthuma) with a moderate result. The result of antibacterial activity revealed that aqueous extract  of leaves and roots showed better activity in comparison to aqueous extracts particularly against gram positive bacteria (Staphylococcus aureus).

Downloads

Download data is not yet available.

References

Vinod D, Rangeri; Pharmacognosy and phytochemistry, text book career publication; volume I.

Geetika Pant and Ugam K. Chauhan; Germination behavior of Cassia toraS eeds in various pre-sowing treatment methods; International Journal of Pharma and Bio Sciences 4(3): (B) 773 – 778. (2013)

Manjusha Choudhary, YuvrajGulia; Nitesh; Cassiatora: Its chemistry, medicinal uses and pharmacology; Pharmacologyonline3: 78-96 (2011).

E. SanmugaPriya,P. SenthamilSelvan& P. P. Prakash; HPTL method development and validation for simultaneous analysis of emodin and chrysophanol in Cassia toralinnmethanolic extract; Journal of Liquid Chromatography & Related Technologies, 36:2525–2533, (2013).

A K Meena, Uttam S Niranjan, A K Yadav, Brijendra Singh, A K Nagariya and M MRao;Cassia toraLinn:A review on its ethnobotany, phytochemical and pharmacological profile;Journal of Pharmacy Research, 3(3)557-560.(2010)

Nayan R. Bhalodia et al. Antibacterial and Antifungal activity from Flower Extracts of Cassia fistula L.: An Ethnomedicinal Plant, Int.J. PharmTech Res, 3(1) 160-168,( 2011)

Dubey RD, Verma S, Rane D, Wani VK, Pandey AK and Paroha S ; Comparative Studies of Anthelmintic Activity of Zingiberofficinale and Cassia tora ,International Journal of Chemical and Pharmaceutical Sciences, 1(1):23-32, (2010).

Abalaka et. al Antibacterial Activities of Azadirachta Indica against Some Bacterial Pathogens, Advances in Life Sciences 2(2): 5-8, (2012).

Nwokonkwo et. al The Phytochemical Study and Antibacterial Activities of the Seed Extract of Dacryodes Edulis (African Native Pear), American Journal of Scientific and Industrial Research 5(1),7-12, (20014).

Deore S. L., S.S.Khadabadi, Kamdi K. S., Ingle V. P., Kawalkar N. G. Sawarkar P. S, Patil U. A, Vyas A. J.,In vitro Anthelmintic activity of Cassia tora ; Int. J. Chem Tech Res1(2) 177-179,( 2009).

Published

2017-12-24

How to Cite

Shrestha, A., Ghimire, K. ., Gupta, A. K., Pokhrel, P., Banerjee, J., Khanal, H., & Pradhananga, M. (2017). Phytochemical screening and antihelminthic activity of leaf and root extracts of Cassia tora plant. Journal of Applied Pharmaceutical Research, 5(4), 22-27. Retrieved from https://japtronline.com/index.php/joapr/article/view/87

Issue

Section

Articles