Standardization of herbal medicines – an overview
Keywords:
Standardization, quality, purity, herbal productsAbstract
In the few decades, there has been exponentional growth in the field of herbal medicines. Most of the traditional systems of medicine are effective due to lack of standardization. So there is a need to develop a standardization technique. Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of the drug. There is increasing awareness and general acceptability of the use herbal drugs in today’s medical practice. The world population depends on herbal medicines and product for healthy living. This rise in the use of herbal product has also given rise to various forms of adulteration of the products, which leading to consumers’ and manufacturers’ disappointment and in some instances fatal consequences. The challenge is innumerable and enormous, to fulfill the need of global herbal market. The standardization of this formulations like the organoleptic characters, physical properties, the various physic-chemical properties such as moisture content, ash values, extractive values need to be carried out along with Thin layer chromatography and heavy metal content study should also carried out to ascertain the quality, purity and safety of this herbal formulation.Downloads
References
Kunle, Folashade O, Egharevba, Omoregie H and Ahmadu, Ochogu P, Standardization of herbal medicines - A review. International Journal of Biodiversity and Conservation, 2012; 4(3): 101-112.
Ekka N R, Namdeo K P and Samal P K, Standardization Strategies for Herbal Drugs-An Overview, Research J. Pharm. and Tech. 2008; 1(4): 310-312.
Chaudhury RR, Herbal medicine for human health. World Health Organization Geneva, CBS publishers and distributors LTD New Delhi, 1999.
Raina MK, Quality control of herbal and herbo-mineral formulations. Indian journal of natural products, 2003; 19: 11-15.
Pravin H, Nikam, Kareparamban J, Jadhav A and Kadam V, Future Trends in Standardization of Herbal Drugs, Journal of Applied Pharmaceutical Science. 2012; 2 (6): 38-44.
Sharma V, Agarwal K, Maithani J and Nanda D. Development of Quality Standards of Vatari Churna: A Polyherbal Formulation, IJPSR, 2012; 3(8): 2870-2872.
Mosihuzzaman M., and Choudhary M I, Protocols on Safety, Efficacy, Standardization, and Documentation of Herbal Medicine, Pure Appl. Chem. 2008; 80(10): 2195–2230.
Nainwal P., Pharmacovigilance of Herbal Medicines: An Intangible Approach, IJPSR, 2010; 1(11): 60-65.
Dixit V.K., Yadav N.P. Recent approaches in herbal drug standardization. Integr Biol. 2008; 2 (3): 195-203.
General guidelines for methodologies on research and evaluation of traditional medicine. Geneva, World Health Organization, 2000 (WHO/EDM/TRM/2000.1)
Zhang X, Twarog S, Kapoor P, traditional medicine: its importance and production and Protecting and promoting traditional knowledge: system, National Experience and International Dimensions, Part 1. The role of traditional knowledge in Helth Care and Agriculture, United nation. New York document. 2002-04; 3-6. UNCTAD/DITC/TED/10.
Gogtay N J, Bhatt H A, Dalvi S S, and Kshirsagar N A, The Use and Safety of Non-Alopathic Indian Medicines, Drug Safety,2002;. 25(14): 1005- 1019.
.Roy A K, Threat to medicinal plants and drugs by fungi. J. Indian Bot. Soc 1989; 68: 149-153.
Dubey N K, Rajesh Kumar and Pramila Tripathi. Global promotion of herbal medicine: India.s opportunity. Current Science 2004; 86 (1): 37-41.
Raghavendra H L,Yogesh H S, Gopalakrishna B, Chandrashekhar V M, Sathish B P, An Overview of Herbal Medicine, Int. J. Ph. Sci, 2009;1(1):1-20
Rudolf B, Quality Criteria and Standardization o f Phytopharmaceuticals: Can Acceptable Drug Standards Be Achieved? Drug Information Journal, 1998; 32: 101–110
Dasgupta P, and De A, Comparative Standardization Study of Two Marketed Ashwagandha Churna Formulation, International Journal of Research in Pharmaceutical and Biomedical Sciences, 2012; 3 (2): 734-741.
Gautam A, Kashyap S J, Sharma P K, Garg V K, Visht S, Kumar N, Identification, evaluation and standardization of herbal drugs: A review, Der Pharmacia Lettre, 2010; 2(6): 302-315
Gatkal S, Punde A, Balap A, and Chaudhari,P, Safety of Herbal Medicine: A Review, International Journal of Pharmaceutical and Chemical Sciences, 2012; 1(4): 1625-1639.
ICDRA. International Conference on Drug Regulatory Authorities, World Health Organization (1986).
Sahoo N, Manchikanti P, Dey S, Herbal drugs: Standards and regulation, Fitoterapia. 2010; 81: 462–471.
Patra K C, Pareta S K, Harwansh R K, Kumar K. J, Traditional approaches towards standardization of herbal medicines -a review, Journal of Pharmaceutical Science and Technology. 2010; 2 (11):372-379
Thirumalai D, Paridhavi M, Gowtham M, An Overview of standardization of herbal drugs, Int.J.Rev.Life Sci, 2011;1(3):167-170.
Shaw P. C., P. P. Butt. Authentication of Panax species and their adulterants by random primed polymerase chain reaction, Planta Med, 1995; 61: 466-469.
Jianga Y., B. David, P. Tu, Y. Barbin. Recent analytical approaches in quality control of traditional Chinese medicines—A review, Anal. Chim. Acta. 2010; 657: 9–18.
Bai C.C., S.Y. Han, X.Y. Chai, Y. Jiang, P. Li, P.F. Tu, Sensitive determination of saponins in Radix et Rhizoma Notoginseng by charged aerosol detector coupled with HPLC, J. Liq. Chromatogr. Relat.Technol. 2009; 32: 242-260.
Myinff S., W. R.W. Daud, A.B. Mohamad, A. A.H. Kadhum. Gas chromatographic determination of eugenol in ethanol extract of cloves, J. Chromatogr. B, 1996; 679: 193-195.
Published
How to Cite
Issue
Section
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.