Formulation and evaluation of colon targeted dosage form of prednisolone tablet using sterculia gum

Authors

  • Neha Singh Raghuvanshi Divison of Pharmaceutical Sciences, Shri Guru Ram Rai Institute of Technology and Science, Dehradun
  • Laxmi Goswami Divison of Pharmaceutical Sciences, Shri Guru Ram Rai Institute of Technology and Science, Dehradun
  • Preeti Kothiyal Divison of Pharmaceutical Sciences, Shri Guru Ram Rai Institute of Technology and Science, Dehradun

Keywords:

Colon targeted, Ethyl Cellulose, Carbopol 934p, Sterculia gum, wet granulation, Crohn’s disease

Abstract

Matrix tablets of Prednisolone were prepared by wet granulation method using various proportions of Sterculia gum with Carbopol 934P and Sterculia gum with Ethyl cellulose at 1:1, 1: .5 and 1:2 ratio. Coating was carried out by using 1:1 ratio of Eudragit L100 and Eudragit S100. All the preparation were evaluated for Pre compressional properties, Post compressional properties and in-vitro Dissolution study in different pH buffer of 0.1N HCL ,pH 7.4 , pH 6.8 in order to mimic GIT condition. Formulation shows good results with good percentage yield.

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References

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Published

2014-09-24

How to Cite

Raghuvanshi, N. S. ., Goswami, L., & Kothiyal, P. (2014). Formulation and evaluation of colon targeted dosage form of prednisolone tablet using sterculia gum. Journal of Applied Pharmaceutical Research, 2(3), 16-19. Retrieved from https://japtronline.com/index.php/joapr/article/view/32

Issue

Vol. 2 No. 3 (2014)

Section

Articles

Copyright (c) 2020 Neha Singh Raghuvanshi, Laxmi Goswami, Preeti Kothiyal

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.