Overview of formulation & evaluation of fast dissolving tablet: A promising tablet dosage form


  • Akash Babu Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (UP), India
  • Md. Semimul Akhtar Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (UP), India




Fast dissolving tablets, Patient’s compliance, Mass extrusion, Super disintegrants, Dysphasia


The science of drug delivery has been increasingly innovative and quick evolving with ever-increasing demand in the current scientific scenario. Fast dissolving tablet (FDT) is one of those forms of an advanced and special drug delivery system that is rapidly gaining a lot of attention in the rapid dissolution technology research sector.

Fast dissolving tablets appear as one of the common and widely accepted dosage types, particularly for paediatric patients due to incomplete muscle and nervous system development and a form of geriatric patients with Parkinson's disease or hand shivering. The most popular administrative path for different medications has drawbacks such as first-pass metabolism, psychotic patients, bedridden and Uncollaborative patients, is the oral delivery type and oral path FDTs disintegrate or quickly dissolve in the saliva without requiring water. Within few seconds, FDT will dissolve within saliva for approximately 60 seconds and these comprises will dissolve even faster


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Nautiyal U, Singh S, Singh R, Gopal KS. Fast dissolving tablets as a novel boon, a review. J Pharm Chem Biol Sci, 2, 5-26 (2014)

Bhowmik D, Chiranjib B, Krishnakanth, P, Chandira RM. Fast dissolving tablet, an overview. J Chem Pharm Res, 1, 163-77 (2009)

Renon, JP, Corveleyn, S. Freeze-dried rapidly disintegrating tablets, US Patent No.6, 010, 719, 2000.

Pebley WS, Jager NE, Thompson SJ. Rapidly disintegrating tablets, US Patent No. 5, 298, 261, 1994.

Abdulraheman ZS, Patel MR, Patel KR. A review on immediate release tablet. Int J Univers Pharm Bio Sci, 3, 93-113 (2014)

Maeda K, Akagi J. Treatment of sarcopenic dysphagia with rehabilitation and nutritional support, a comprehensive approach. Journal of the Academy of Nutrition and Dietetics, 116, 573-7 (2016)

Siddiqui N, Garg G, Sharma PK. Fast dissolving tablets, preparation, characterization and evaluation, an overview. Int J Pharm Sci Rev Res, 2, 87-96 (2010)

Mishra US, Prajapati SK, Bhardwaj P. A review on formulation and evaluation for mouth dissolving tablet. World J Pharm Pharm Sci, 8, 1778-810 (2014)

Arya A, Chandra A, Fast drug delivery system: A review. Scholars Research Library, 2(2), 350-361 (2010)

Kaur T, Gill B, Kumar S, Gupta GD. Mouth dissolving tablets, a novel approach to drug delivery. Int J Curr Pharm Res, 1, 1-7 (2011)

Debjit, B., Chiranjib, B., Krishnakanth, Pankaj, R.Margret Chandira, Fast Dissolving Tablet, An Overview,J Chemical and Pharma Res 1(1), 163-177 (2009)

Gupta DK, Bajpai M, Chatterjee DP. Fast mouth is dissolving disintegrating tablet and patient counselling points for FDDTS: a review. Int J Res Dev Pharm L Sci, 3, 949-58 (2014)

Ghosh TK, Pfister WR (Eds), Drug Delivery to the Oral Cavity, Molecules to Market, NY, USA, CRC Press, 2005, 337-356.

Habib W, Khankari R, Hontz J. Fast-dissolving drug delivery system. Crit. Rev. Ther. Drug Carrier Syst, 17, 61–72 (2000)

Seager H. Drug delivery products and the Zydis fast-dissolving dosages forms, J Pharma Pharmacol 50,375-82 (1998)

Behnke K, Sogaard J, Marcin BSJ, Ravindran AV, Agren H, et al. Mircazapine Orally disintegrating tablet versus sertraline. A prospective onset of action study, J Clin Psychopharmacol, 23, 358-64 (2003)

Kaur T, Gill B, Kumar S, Gupta GD. Mouth Dissolving Tablets, A Novel Approach to Drug Delivery. International Journal of Current Pharmaceutical Research 03(1), 1-7 (2011)

Basu B, Bagadiya A, Makwana S, Vora V, Batt D, Dharamsi, A. Formulation and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material,J Advanced Pharma Tech & Res, 2(4), 266-73 (2011)

Kundu S, Sahoo P. K. Recent Trends In The Developments of Orally Disintegrating Tablet Technology. Pharma Times, 40(4), 11-15 (2008)

Bandari S, Gannu R, Orodispersible Tablets, An Overview, Asian Journal of Pharmaceutics, 2-10 (2008)

Shukla D, Chakraborty S, Singh S, Mishra B. Mouth Dissolving Tablets I, An Overview of Formulation Technology. Scientia Pharmaceutica, 77(2), 309–326 (2009)

Bircan Y, Comoglu T. Formulation technologies of orally fast disintegrating tablets. Marmara Pharm J 16(1), 77-81 (2012)

Sharma R, Rajput M, Prakash P, Sharma S. Fast dissolving drug delivery system, A Review. Int Res J Pharm 2(11), 21-29 (2011)

Rai RR, Chirra P, Thanda V. Fast dissolving tablets, A novel approach to drug delivery–A Review. Int J Preclinical and Pharma Res 3(1), 23-32 (2012)

Parkash V, Maan S, Deepika, Yadav SK, Hemlata, Jogpal V. Fast disintegrating tablets, opportunity in drug delivery system. J Adv Pharm Technol Res 2, 223-35 (2011)

Chowdary YA, Soumya M, Madhubabu M, Aparna K, Himabindu P. A review on fast dissolving drug delivery systems-A pioneering drug delivery technology. Bulletin of Environment, Pharmacology and Life Sciences 1, 8-20 (2012)

Shukla D, Chakraborty S, Singh S, Mishra B. An overview of formulation of mouth dissolving tablets. Sci Pharm 77, 309-26 (2009)

Menat AK, Patel MS, Patel MR, Patel NM. Fast dissolving tablets a novel approach to drug delivery. Asian J Pharm Sci Res 2, 13-21 (2012)

Badguja BP, Mundada AS. The technologies used for developing orally disintegrating tablets, a review. Acta Pharm 61, 117–39 (2011)

Orally Disintegrating Tablets: The Effect of Recent FDA Guidance on ODT Technologies and Applications, https://www.pharmtech.com/view/allegations-put-kodak-pharmaceuticals-loan-on-hold cited 22 November 2020

Nagar P, Singh K, Chauhan I, Verma M, Yasir M, Khan A. Orally disintegrating tablets, formulation, preparation techniques and evaluation. J Appl Pharma Sci 1, 35-45 (2011)

Patel R, Prajapati S, Raval A. Fast dissolving films (FDFs) as a newer venture in fast dissolving dosage forms. Int J Drug Dev & Res 2010, 2(2): 232-236.

Orally Disintegrating Tablets https://www.pharmtech.com/view/orally-disintegrating-tablets-1 cited 26 November 2020

Khemariya P, Gajbhiye KR, Vaidya VD, Jadon RS, Mishra S, Shukla A, Bhargava M, Singhai SK, Goswami S. Preparation and evaluation of mouth dissolving tablets of meloxicam. Int. J. Drug Delivery 2, 76–80 (2010)

Baghel P, Roy A, Chandrakar S, Bahadur S. Fast Dissolving Drug Delivery Systems: A Brief Review. Res. J. Pharm. Technol., 6, 597–602 (2013).

Ashish P, Harsoliya MS, Pathan JK, Shruti S. A review: formulation of mouth dissolving tablet. Int J Pharm Res 1, 1-8 (2011)



How to Cite

Akash Babu, & Akhtar, M. S. (2020). Overview of formulation & evaluation of fast dissolving tablet: A promising tablet dosage form. Journal of Applied Pharmaceutical Research, 8(3), 01-09. https://doi.org/10.18231/j.joapr.2020.v.8.i.3.1.9