Evaluation of analgesic and anti-inflammatory activity of ethanolic extract of Enhydra fluctuans on male wistar rats


  • Kishor Kumar Roy Department of Pharmacology, Bharat Technology, Uluberia, Howrah, West Bengal
  • Md. Kabirul Islam Mollah Department of Pharmacology, Bharat Technology, Uluberia, Howrah, West Bengal
  • Md. Masud Reja Mata Gujri College of Pharmacy, Kishanganj, Bihar
  • Dibyendu Shil Mata Gujri College of Pharmacy, Kishanganj, Bihar
  • Ranjan Kumar Maji Department of Pharmacology, Bharat Technology, Uluberia, Howrah, West Bengal




Enhydra fluctuans, Eddy’s hot plate, formalin, paw edema, analgesic, anti-inflammatory


Enhydra fluctuations an edible semi-aquatic vegetable plant are widely used in the traditional system of medicine. Ethanolic extract of Enhydra fluctuans was screened for analgesic & anti-inflammatory activity. Analgesic activity was evaluated by the hot plate method and anti-inflammatory activity was evaluated by formalin induce paw edema in Wistar rats (male). Ethanolic extract dose of 300 mg/kg reduce formalin induce paw inflammation and also increased the pain threshold in rats evidenced by hot plate method. The experimental results concluded that Enhydra fluctuans have significant analgesic and anti-inflammatory activity may due to flavonoid and phenolic compound content.


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How to Cite

Roy, K. K., Mollah, M. K. I., Reja, M. M., Shil, D. ., & Maji, R. K. (2021). Evaluation of analgesic and anti-inflammatory activity of ethanolic extract of Enhydra fluctuans on male wistar rats . Journal of Applied Pharmaceutical Research, 9(1), 37-42. https://doi.org/10.18231/JOAPR.2021.