Journal of Applied Pharmaceutical Research 2020-06-13T04:02:55+0530 Dr. Sanjib Bahadur Open Journal Systems <p><em><strong>Journal of Applied Pharmaceutical Research (JOAPR),</strong> <strong>ISSN No. 2348-0335</strong></em> is an official publication of Creative Pharma Assent (CPA). It is an open access, peer reviewed online Journal. JOAPR primarily focuses on publication of manuscript related to multiple disciplines of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, Biopharmaceutics, Cosmetic Technology, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Herbal drugs/ formulations, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy). JOAPR is published quarterly. JOAPR also includes evaluation of pharmaceutical excipients &amp; their practical application to research &amp; industry based efforts. The aim of the scientific journal, JOAPR is to present a wide area for the current researchers to share their noble works and ideas in terms of the research papers, review articles and short communications. JOAPR only publishes original research works with a definite innovation and novelty after thorough plagiarism checking and peer reviewing. The paper must have a suitable and proper scientific background.</p> <p><strong>Brief Information about JOAPR</strong></p> <ul> <li><strong>Journal Title: </strong>Journal of Applied Pharmaceutical Research</li> <li><strong>Journal Abbreviation: </strong>J. Appl. Pharm. Res.</li> <li><strong>Publisher: </strong>Creative Pharma Assent</li> <li><strong>Country: </strong>India</li> <li><strong>Language: </strong>English</li> <li><strong>Publishing Frequency: </strong>Quarterly</li> <li><strong>Editor In Chief:</strong> Prof. Amit Roy</li> <li><strong>Editorial Office: </strong>Plot No. 105/42, Opposite electricity sub station, Changorabhata, Raipur (CG) 492001, India</li> <li><strong>Regional Office:</strong> Bishnupath, Rukminigoan, Dispur, Guwahati, Assam, PIN-781022</li> <li><strong>Phone: </strong>+91-8349444385 ; +91-9770019143</li> <li><strong>E-mail: </strong> ;</li> <li><strong>Website: </strong></li> <li><strong>Publication: </strong>Online only</li> <li><strong>e-ISSN: </strong>2348-0335</li> <li><strong>CODEN: </strong>JAPRIV</li> <li><strong>Year of Start: </strong>2013</li> <li><strong>Review Process</strong><strong>: </strong>Double-blind peer review</li> </ul> Autism: a curse on today’s society 2020-06-12T06:16:28+0530 Snehashis Sarkar Ananta Choudhury Suman Saha Biplab Kumar Dey <p>Autism is a group of neurodevelopment disorders characterized by impaired communication, impaired social interaction and restricted, repetitive and stereotyped patterns of behaviours or interests in the first 3 years of life. It shows a strong male bias and found four times more in males than in females. According to a study in the US, in 2014, overall 1.68% of victims were reported to have Autism Spectrum Disorder (ASD), whereas the percentage was increased by 15% and 150% respectively over the year 2012 and 2000. Numerous genes have been discovered that have roles in ASD but still a good understanding of the pathophysiological process of ASD is not established. ASD costs are estimated to be approximately $250 billion annually in the U.S. Moreover, it is suggested that by 2025, ASD costs will rise to over $450 billion. Thus, the financial burden on families is increasing. There is no effective screening tool for proper diagnosis is available. Based on Infant Toddler Checklist (ITC) and Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) some tests like ADOS-G, ADI-R, CARS etc. are used for diagnosis. There are medications to cure symptoms but no single medication for ASD. However, some therapies (like ABA- Applied Behavioural Analysis, DTT- Discrete Trial Training, and Symptomatic treatments, etc.) are there that show positive responses towards improvement from a disease state. Some crucial advancement has been achieved in the last decades. Here in the work we have focused on the diagnostic methods and treatment available for the symptoms of Autism. So, it can be said that the day is not too far away when the remedy to cut the curse of autism will be in our hands.</p> 2020-03-30T00:00:00+0530 Copyright (c) 2020 Snehashis Sarkar, Ananta Choudhury, Suman Saha, Biplab Kumar Dey A review on the current drugs and new targets for obesity 2020-06-12T06:34:56+0530 M J Poojashree H S Siddalingaprasad B R Swetha Shivukumar Swamy <p>Obesity is defined as the condition in which the Body Mass Index (BMI) of an individual is between 25 and 29.5 that is ≥30kg/m<sup>2</sup> and is caused by the imbalance management of energy intake and expenditure. Obesity is among the most prevalent diseases in the world and approximately over 10% of the people belong to overweight group in the world and over 5% in India.&nbsp; Currently many drugs are used to treat or to manage obesity. But these drugs also account for several side effects. So there is an extensive need of promising drugs which can control obesity with greater efficacy and economic viability. This review focusses on the current drugs in the market used to treat obesity and also few of the new probable targets to discover drugs</p> 2020-03-30T00:00:00+0530 Copyright (c) 2020 M J Poojashree, H S Siddalingaprasad, B R Swetha , Shivukumar Swamy Liposome: a carrier for effective drug delivery 2020-06-12T06:59:09+0530 Ananta Choudhury Kashmiri Sonowal Rahela E Laskar Debasish Deka Biplab Kumar Dey <p>Liposomes are the spherical vesicles containing one or more phospholipid bilayer, which was first described in the middle of 60s by Bangham. The bilayer vesicles are considered as an efficient carrier for drug delivery, diagnostic agents, and also an effective tool for vaccine delivery.&nbsp; Liposome has been used as a potential carrier for several diseases from cardiovascular disease to bacterial infection and also it has the ability to reducing the toxicity of highly potent drugs and simultaneously utilized to improve pharmacokinetics and therapeutic efficacy. A liposome is a formulation which has the capacity to overcome with the limitation of conventional therapies. For the delivery of liposome ocular and inhalation route are some advanced technology. In poorly water soluble substance pulmonary delivery is very much useful. However liposome based vaccines have been demonstrated in clinical trials and further progress in human trails. This review discusses the mechanism of action, Method of preparation, evaluation, application of liposomal drug delivery system along with the recent developments some of the commercially available products.</p> 2020-03-30T00:00:00+0530 Copyright (c) 2020 Ananta Choudhury, Kashmiri Sonowal, Suman Saha, Biplab Kumar Dey Development, standardization of polyherbal formulation of analgesic ointment of plant Carum copticum, Mentha piperita, Cedrus deodara 2020-06-13T04:02:55+0530 Sharad Sharma Sonu Sharma Pankaj Pradhan Shailesh Pathak Monika Sharma <p>Ayurveda is one of the world’s oldest systems of medicine. It originated in India and has evolved there over thousands of years. The term “Ayurveda” combines then Sanskrit words ayur (life) andVeda (science or knowledge). Ayurveda means “the science of life. Medicinal plants and herbal drugs have played a key role in world health. According to world health organization (WHO), about 80% of the world population currently utilizes the herbal drugs. People are using herbal medicines from centuries for safety, efficacy, cultural acceptability, non-toxic, lesser side effects and easily available at affordable prices. In recent times, there has been a move in universal trend from synthetic to herbal medicine due to side effects of synthetic products. Herbal products may contain a single herb or combinations of several different herbs believed to have complementary and /synergistic effects. Some herbal products, including many traditional medicine formulations, also include animal products and minerals. Herbal products are sold as either raw plants or extracts of portions of the plant or in the form formulation i.e. tablet, capsule, syrup, cream and ointment etc. The different parts of plants with analgesic were taken up for the present study and investigated for the phytochemical screening and used for the formulation of analgesic ointment. Present study deals with formulation, Standardization, evaluation of ointment made from alcoholic extract and essential oil of different plants.</p> 2020-03-30T00:00:00+0530 Copyright (c) 2020 Sharad Sharma, Sonu Sharma, Pankaj Pradhan, Shailesh Pathak, Monika Sharma